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T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus
JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a life-threatening brain disease in immunocompromised patients. Inherited and acquired T cell deficiencies are associated with PML. The incidence of PML is increasing with the introduction of new immunomodulatory agents...
Autores principales: | Lauver, Matthew D, Jin, Ge, Ayers, Katelyn N, Carey, Sarah N, Specht, Charles S, Abendroth, Catherine S, Lukacher, Aron E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674346/ https://www.ncbi.nlm.nih.gov/pubmed/36341713 http://dx.doi.org/10.7554/eLife.83030 |
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