Cargando…

Integrative modeling reveals the molecular architecture of the intraflagellar transport A (IFT-A) complex

Intraflagellar transport (IFT) is a conserved process of cargo transport in cilia that is essential for development and homeostasis in organisms ranging from algae to vertebrates. In humans, variants in genes encoding subunits of the cargo-adapting IFT-A and IFT-B protein complexes are a common caus...

Descripción completa

Detalles Bibliográficos
Autores principales: McCafferty, Caitlyn L, Papoulas, Ophelia, Jordan, Mareike A, Hoogerbrugge, Gabriel, Nichols, Candice, Pigino, Gaia, Taylor, David W, Wallingford, John B, Marcotte, Edward M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674347/
https://www.ncbi.nlm.nih.gov/pubmed/36346217
http://dx.doi.org/10.7554/eLife.81977