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A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology

Neuroscience currently requires the use of antibodies to study synaptic proteins, where antibody binding is used as a correlate to define the presence, plasticity, and regulation of synapses. Gephyrin is an inhibitory synaptic scaffolding protein used to mark GABAergic and glycinergic postsynaptic s...

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Detalles Bibliográficos
Autores principales: Campbell, Benjamin FN, Dittmann, Antje, Dreier, Birgit, Plückthun, Andreas, Tyagarajan, Shiva K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674349/
https://www.ncbi.nlm.nih.gov/pubmed/36314779
http://dx.doi.org/10.7554/eLife.80895