DNA-Stimulated Liquid-Liquid phase separation by eukaryotic topoisomerase ii modulates catalytic function

Type II topoisomerases modulate chromosome supercoiling, condensation, and catenation by moving one double-stranded DNA segment through a transient break in a second duplex. How DNA strands are chosen and selectively passed to yield appropriate topological outcomes – for example, decatenation vs. ca...

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Detalles Bibliográficos
Autores principales: Jeong, Joshua, Lee, Joyce H, Carcamo, Claudia C, Parker, Matthew W, Berger, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674351/
https://www.ncbi.nlm.nih.gov/pubmed/36342377
http://dx.doi.org/10.7554/eLife.81786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674351/
https://www.ncbi.nlm.nih.gov/pubmed/36342377
http://dx.doi.org/10.7554/eLife.81786

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