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Human pericytes degrade diverse α-synuclein aggregates

Parkinson’s disease (PD) is a progressive, neurodegenerative disorder characterised by the abnormal accumulation of α-synuclein (α-syn) aggregates. Central to disease progression is the gradual spread of pathological α-syn. α-syn aggregation is closely linked to progressive neuron loss. As such, cle...

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Detalles Bibliográficos
Autores principales: Dieriks, Birger Victor, Highet, Blake, Alik, Ania, Bellande, Tracy, Stevenson, Taylor J., Low, Victoria, Park, Thomas I-H, Correia, Jason, Schweder, Patrick, Faull, Richard L. M., Melki, Ronald, Curtis, Maurice A., Dragunow, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674377/
https://www.ncbi.nlm.nih.gov/pubmed/36399706
http://dx.doi.org/10.1371/journal.pone.0277658