Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade

Arrhythmogenic cardiomyopathy (ACM) is characterized by progressive loss of cardiomyocytes with fibrofatty tissue replacement, systolic dysfunction, and life-threatening arrhythmias. A substantial proportion of ACM is caused by mutations in genes of the desmosomal cell–cell adhesion complex, but the...

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Detalles Bibliográficos
Autores principales: Schinner, Camilla, Xu, Lifen, Franz, Henriette, Zimmermann, Aude, Wanuske, Marie-Therès, Rathod, Maitreyi, Hanns, Pauline, Geier, Florian, Pelczar, Pawel, Liang, Yan, Lorenz, Vera, Stüdle, Chiara, Maly, Piotr I., Kauferstein, Silke, Beckmann, Britt M., Sheikh, Farah, Kuster, Gabriela M., Spindler, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674449/
https://www.ncbi.nlm.nih.gov/pubmed/36268721
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.057329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674449/
https://www.ncbi.nlm.nih.gov/pubmed/36268721
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.057329

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