The genetic landscape of major drug metabolizing cytochrome P450 genes—an updated analysis of population-scale sequencing data

Genes encoding cytochrome P450 enzymes (CYPs) are extremely polymorphic and multiple CYP variants constitute clinically relevant biomarkers for the guidance of drug selection and dosing. We previously reported the distribution of the most relevant CYP alleles using population-scale sequencing data....

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Detalles Bibliográficos
Autores principales: Zhou, Yitian, Lauschke, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674520/
https://www.ncbi.nlm.nih.gov/pubmed/36068297
http://dx.doi.org/10.1038/s41397-022-00288-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674520/
https://www.ncbi.nlm.nih.gov/pubmed/36068297
http://dx.doi.org/10.1038/s41397-022-00288-2

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