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Calmodulin-dependent protein kinase II activation promotes kidney mesangial expansion in streptozotocin-induced diabetic mice()
Calcium-calmodulin-dependent protein kinase II (CaMKII) is upregulated in diabetes mellitus (DM), leading to the overproduction of collagen in the myocardium. We hypothesized that CaMKII plays a role in the development of diabetic nephropathy (DN). Streptozotocin (STZ) injection into FVB wild-type m...
Autores principales: | Mikhailov, Alexei V., Liu, Yixi, Cheng, Heng-Jie, Lin, Jen-Jar, Cheng, Che Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674542/ https://www.ncbi.nlm.nih.gov/pubmed/36411910 http://dx.doi.org/10.1016/j.heliyon.2022.e11653 |
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