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Loss of myeloid Tsc2 predisposes to angiotensin II-induced aortic aneurysm formation in mice

RATIONALE: Genetic studies have proved the involvement of Tuberous sclerosis complex subunit 2 (Tsc2) in aortic aneurysm. However, the exact role of macrophage Tsc2 in the vascular system remains unclear. Here, we examined the potential function of macrophage Tsc2 in the development of aortic remode...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Liu, Yan, Yang, Rui-xue, Ding, Xiang-jiu, Liang, Er-shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674579/
https://www.ncbi.nlm.nih.gov/pubmed/36400753
http://dx.doi.org/10.1038/s41419-022-05423-2