Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo

Infantile fibrosarcoma is a rare childhood tumour that originates in the fibrous connective tissue of the long bones for which there is an urgent need to identify novel therapeutic targets. This study aims to clarify the role of the extracellular matrix component hyaluronan in the invasion of child...

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Detalles Bibliográficos
Autores principales: Tonge, Joseph J., Notley, Scott V., Dunning, Mark J., López-Guajardo, Ana, Medcalf, Jessica D., Heldin, Paraskevi, Panoutsos, George, Gad, Annica K. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674583/
https://www.ncbi.nlm.nih.gov/pubmed/36400790
http://dx.doi.org/10.1038/s41598-022-21952-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674583/
https://www.ncbi.nlm.nih.gov/pubmed/36400790
http://dx.doi.org/10.1038/s41598-022-21952-4

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