Cargando…
Prioritizing autoimmunity risk variants for functional analyses by fine-mapping mutations under natural selection
Pathogen-driven selection shaped adaptive mutations in immunity genes, including those contributing to inflammatory disorders. Functional characterization of such adaptive variants can shed light on disease biology and past adaptations. This popular idea, however, was difficult to test due to challe...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674589/ https://www.ncbi.nlm.nih.gov/pubmed/36400766 http://dx.doi.org/10.1038/s41467-022-34461-9 |