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Co-aggregation of MSC/chondrocyte in a dynamic 3D culture elevates the therapeutic effect of secreted extracellular vesicles on osteoarthritis in a rat model

Extracellular vesicles (EVs) have therapeutic effects on osteoarthritis (OA). Some recent strategies could elevate EV's therapeutic properties including cell aggregation, co-culture, and 3D culture. It seems that a combination of these strategies could augment EV production and therapeutic pote...

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Detalles Bibliográficos
Autores principales: Esmaeili, Abazar, Hosseini, Samaneh, Kamali, Amir, Hosseinzadeh, Maryam, Shekari, Faezeh, Baghaban Eslaminejad, Mohamadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674636/
https://www.ncbi.nlm.nih.gov/pubmed/36400827
http://dx.doi.org/10.1038/s41598-022-22592-4