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A Myb enhancer-guided analysis of basophil and mast cell differentiation

The transcription factor MYB is a crucial regulator of hematopoietic stem and progenitor cells. However, the nature of lineage-specific enhancer usage of the Myb gene is largely unknown. We identify the Myb −68 enhancer, a regulatory element which marks basophils and mast cells. Using the Myb −68 en...

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Detalles Bibliográficos
Autores principales: Matsumura, Takayoshi, Totani, Haruhito, Gunji, Yoshitaka, Fukuda, Masahiro, Yokomori, Rui, Deng, Jianwen, Rethnam, Malini, Yang, Chong, Tan, Tze King, Karasawa, Tadayoshi, Kario, Kazuomi, Takahashi, Masafumi, Osato, Motomi, Sanda, Takaomi, Suda, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674656/
https://www.ncbi.nlm.nih.gov/pubmed/36400777
http://dx.doi.org/10.1038/s41467-022-34906-1