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A Myb enhancer-guided analysis of basophil and mast cell differentiation
The transcription factor MYB is a crucial regulator of hematopoietic stem and progenitor cells. However, the nature of lineage-specific enhancer usage of the Myb gene is largely unknown. We identify the Myb −68 enhancer, a regulatory element which marks basophils and mast cells. Using the Myb −68 en...
Autores principales: | Matsumura, Takayoshi, Totani, Haruhito, Gunji, Yoshitaka, Fukuda, Masahiro, Yokomori, Rui, Deng, Jianwen, Rethnam, Malini, Yang, Chong, Tan, Tze King, Karasawa, Tadayoshi, Kario, Kazuomi, Takahashi, Masafumi, Osato, Motomi, Sanda, Takaomi, Suda, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674656/ https://www.ncbi.nlm.nih.gov/pubmed/36400777 http://dx.doi.org/10.1038/s41467-022-34906-1 |
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