Cargando…

A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1

Anti-CRISPRs (Acrs) are natural inhibitors of bacteria’s CRISPR-Cas systems, and have been developed as a safeguard to reduce the off-target effects of CRISPR gene-editing technology. Acrs can directly bind to CRISPR-Cas complexes and inhibit their activities. However, whether this process is under...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yanan, Hu, Jiaojiao, Yang, Shan-Shan, Zhong, Jing, Liu, Jianping, Wang, Shuo, Jiao, Yuzhuo, Jiang, Fang, Zhai, Ruiyang, Ren, Bingnan, Cong, Hua, Zhu, Yuwei, Han, Fengtong, Zhang, Jixian, Xu, Yue, Huang, Zhiwei, Zhang, Shengnan, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674691/
https://www.ncbi.nlm.nih.gov/pubmed/36400778
http://dx.doi.org/10.1038/s41467-022-34551-8