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The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles

Contraction of striated muscle is regulated by a dual mechanism involving both thin, actin-containing filament and thick, myosin-containing filament. Thin filament is activated by Ca(2+) binding to troponin, leading to tropomyosin displacement that exposes actin sites for interaction with myosin mot...

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Detalles Bibliográficos
Autores principales: Caremani, Marco, Marcello, Matteo, Morotti, Ilaria, Pertici, Irene, Squarci, Caterina, Reconditi, Massimo, Bianco, Pasquale, Piazzesi, Gabriella, Lombardi, Vincenzo, Linari, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674696/
https://www.ncbi.nlm.nih.gov/pubmed/36400920
http://dx.doi.org/10.1038/s42003-022-04184-0