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The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles
Contraction of striated muscle is regulated by a dual mechanism involving both thin, actin-containing filament and thick, myosin-containing filament. Thin filament is activated by Ca(2+) binding to troponin, leading to tropomyosin displacement that exposes actin sites for interaction with myosin mot...
Autores principales: | Caremani, Marco, Marcello, Matteo, Morotti, Ilaria, Pertici, Irene, Squarci, Caterina, Reconditi, Massimo, Bianco, Pasquale, Piazzesi, Gabriella, Lombardi, Vincenzo, Linari, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674696/ https://www.ncbi.nlm.nih.gov/pubmed/36400920 http://dx.doi.org/10.1038/s42003-022-04184-0 |
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