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Delivery of the reduced form of vitamin K(2(20)) to NIH/3T3 cells partially protects against rotenone induced cell death

Mitochondria generate energy through the action of the electron transport chain (ETC) and ATP synthase. Mitochondrial malfunction can lead to various disorders, including neurodegenerative diseases. Several reports have shown that menaquinone-4 (MK-4, vitamin K(2(20))), a safe drug for osteoporosis,...

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Detalles Bibliográficos
Autores principales: Toki, Erina, Goto, Shotaro, Setoguchi, Shuichi, Terada, Kazuki, Watase, Daisuke, Yamakawa, Hirofumi, Yamada, Ayano, Koga, Mitsuhisa, Kubota, Kaori, Iwasaki, Katsunori, Karube, Yoshiharu, Matsunaga, Kazuhisa, Takata, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674836/
https://www.ncbi.nlm.nih.gov/pubmed/36400879
http://dx.doi.org/10.1038/s41598-022-24456-3