Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration

Myoblast fusion is fundamental for the development of multinucleated myofibers. Evolutionarily conserved proteins required for myoblast fusion include RAC1 and its activator DOCK1. In the current study we analyzed the contribution of the DOCK1-interacting ELMO scaffold proteins to myoblast fusion. W...

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Detalles Bibliográficos
Autores principales: Tran, Viviane, Nahlé, Sarah, Robert, Amélie, Desanlis, Inès, Killoran, Ryan, Ehresmann, Sophie, Thibault, Marie-Pier, Barford, David, Ravichandran, Kodi S., Sauvageau, Martin, Smith, Matthew J., Kmita, Marie, Côté, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674853/
https://www.ncbi.nlm.nih.gov/pubmed/36400788
http://dx.doi.org/10.1038/s41467-022-34806-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674853/
https://www.ncbi.nlm.nih.gov/pubmed/36400788
http://dx.doi.org/10.1038/s41467-022-34806-4

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