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Are targeted therapies or immunotherapies effective in metastatic pancreatic adenocarcinoma?
Metastatic pancreatic ductal adenocarcinoma (PDAC) is a major health burden due to its increasing incidence and poor prognosis. PDAC is characterized by a low tumor mutational burden, and its molecular pathogenesis is driven by Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations. Response to...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674888/ https://www.ncbi.nlm.nih.gov/pubmed/36399952 http://dx.doi.org/10.1016/j.esmoop.2022.100638 |