The construction of cross-population polygenic risk scores using transfer learning

As most existing genome-wide association studies (GWASs) were conducted in European-ancestry cohorts, and as the existing polygenic risk score (PRS) models have limited transferability across ancestry groups, PRS research on non-European-ancestry groups needs to make efficient use of available data...

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Detalles Bibliográficos
Autores principales: Zhao, Zhangchen, Fritsche, Lars G., Smith, Jennifer A., Mukherjee, Bhramar, Lee, Seunggeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674947/
https://www.ncbi.nlm.nih.gov/pubmed/36240765
http://dx.doi.org/10.1016/j.ajhg.2022.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674947/
https://www.ncbi.nlm.nih.gov/pubmed/36240765
http://dx.doi.org/10.1016/j.ajhg.2022.09.010

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