Cargando…
The construction of cross-population polygenic risk scores using transfer learning
As most existing genome-wide association studies (GWASs) were conducted in European-ancestry cohorts, and as the existing polygenic risk score (PRS) models have limited transferability across ancestry groups, PRS research on non-European-ancestry groups needs to make efficient use of available data...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674947/ https://www.ncbi.nlm.nih.gov/pubmed/36240765 http://dx.doi.org/10.1016/j.ajhg.2022.09.010 |