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mRNA lipid nanoparticle phase transition

Crucial for mRNA-based vaccines are the composition, structure, and properties of lipid nanoparticles (LNPs) as their delivery vehicle. Using all-atom molecular dynamics simulations as a computational microscope, we provide an atomistic view of the structure of the Comirnaty vaccine LNP, its molecul...

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Detalles Bibliográficos
Autores principales: Trollmann, Marius F.W., Böckmann, Rainer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674992/
https://www.ncbi.nlm.nih.gov/pubmed/36045573
http://dx.doi.org/10.1016/j.bpj.2022.08.037