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Strain stiffening of Ndc80 complexes attached to microtubule plus ends

In the mitotic spindle, microtubules attach to chromosomes via kinetochores. The microtubule-binding Ndc80 complex is an integral part of kinetochores, and is essential for kinetochores to attach to microtubules and to transmit forces from dynamic microtubule ends to the chromosomes. The Ndc80 compl...

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Detalles Bibliográficos
Autores principales: Schwietert, Felix, Volkov, Vladimir A., Huis in ’t Veld, Pim J., Dogterom, Marileen, Musacchio, Andrea, Kierfeld, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675032/
https://www.ncbi.nlm.nih.gov/pubmed/36199251
http://dx.doi.org/10.1016/j.bpj.2022.09.039