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CircGSAP alleviates pulmonary microvascular endothelial cells dysfunction in pulmonary hypertension via regulating miR-27a-3p/BMPR2 axis

BACKGROUND: Our previous study showed that circular RNA-gamma-secretase-activating protein (circGSAP) was down-regulated in pulmonary microvascular endothelial cells (PMECs) in response to hypoxia, and regulated the cell cycle of PMECs via miR-942-5p sponge in pulmonary hypertension (PH). However, t...

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Detalles Bibliográficos
Autores principales: Sun, Yuanyuan, Jiang, Rong, Hu, Xiaoyi, Gong, Sugang, Wang, Lan, Wu, Wenhui, Li, Jinling, Kang, Xinyang, Xia, Shijin, Liu, Jinming, Zhao, Qinhua, Yuan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675109/
https://www.ncbi.nlm.nih.gov/pubmed/36403044
http://dx.doi.org/10.1186/s12931-022-02248-7