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Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions
BACKGROUND: The relative contributions of genetic and environmental factors versus unavoidable stochastic risk factors to the variation in cancer risk among tissues have become a widely-discussed topic. Some claim that the stochastic effects of DNA replication are mainly responsible, others believe...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675110/ https://www.ncbi.nlm.nih.gov/pubmed/36402971 http://dx.doi.org/10.1186/s12885-022-10219-w |