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Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions

BACKGROUND: The relative contributions of genetic and environmental factors versus unavoidable stochastic risk factors to the variation in cancer risk among tissues have become a widely-discussed topic. Some claim that the stochastic effects of DNA replication are mainly responsible, others believe...

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Detalles Bibliográficos
Autores principales: Liu, Xinhui, Yang, Jifeng, Li, Hongkai, Wang, Qing, Yu, Yuanyuan, Sun, Xiaoru, Si, Shucheng, Hou, Lei, Liu, Lu, Yang, Fan, Yan, Ran, Yu, Yifan, Fu, Zhentao, Lu, Zilong, Li, Dejin, Xue, Hao, Guo, Xiaolei, Xue, Fuzhong, Ji, Xiaokang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675110/
https://www.ncbi.nlm.nih.gov/pubmed/36402971
http://dx.doi.org/10.1186/s12885-022-10219-w