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Methods for handling missing data in serially sampled sputum specimens for mycobacterial culture conversion calculation

BACKGROUND: The occurrence and timing of mycobacterial culture conversion is used as a proxy for tuberculosis treatment response. When researchers serially sample sputum during tuberculosis studies, contamination or missed visits leads to missing data points. Traditionally, this is managed by ignori...

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Detalles Bibliográficos
Autores principales: Malatesta, Samantha, Weir, Isabelle R., Weber, Sarah E., Bouton, Tara C., Carney, Tara, Theron, Danie, Myers, Bronwyn, Horsburgh, C. Robert, Warren, Robin M., Jacobson, Karen R., White, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675206/
https://www.ncbi.nlm.nih.gov/pubmed/36402979
http://dx.doi.org/10.1186/s12874-022-01782-8