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Targeted blocking of CCR2 and CXCR2 improves the efficacy of transarterial chemoembolization of hepatocarcinoma

BACKGROUND: Transarterial chemoembolization (TACE) has been shown to prolong survival in patients with unresectable hepatocellular carcinoma (HCC); however, the long-term survival remains dismal. Targeting macrophage and neutrophil infiltration is a promising strategy. The CCL2/CCR2 and CXCLs/CXCR2...

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Detalles Bibliográficos
Autores principales: Tian, Zhiqiang, Hou, Xiaojuan, Liu, Wenting, Shao, Changchun, Gao, Lu, Jiang, Jinghua, Zhang, Li, Han, Zhipeng, Wei, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675208/
https://www.ncbi.nlm.nih.gov/pubmed/36403057
http://dx.doi.org/10.1186/s12935-022-02771-z