ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways

PURPOSE: Long-term glucocorticoid- usage can lead to glucocorticoid-induced osteoporosis (GIOP). The study focused on the preventative effects of a novel active vitamin D3 analog, eldecalcitol (ED-71), against GIOP and explored the underlying molecular mechanisms. METHODS: Intraperitoneal injection...

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Detalles Bibliográficos
Autores principales: Rong, Xing, Kou, Yuying, Zhang, Yuan, Yang, Panpan, Tang, Rong, Liu, Hongrui, Li, Minqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675334/
https://www.ncbi.nlm.nih.gov/pubmed/36411860
http://dx.doi.org/10.2147/DDDT.S377001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675334/
https://www.ncbi.nlm.nih.gov/pubmed/36411860
http://dx.doi.org/10.2147/DDDT.S377001

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