Cargando…
ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways
PURPOSE: Long-term glucocorticoid- usage can lead to glucocorticoid-induced osteoporosis (GIOP). The study focused on the preventative effects of a novel active vitamin D3 analog, eldecalcitol (ED-71), against GIOP and explored the underlying molecular mechanisms. METHODS: Intraperitoneal injection...
Autores principales: | Rong, Xing, Kou, Yuying, Zhang, Yuan, Yang, Panpan, Tang, Rong, Liu, Hongrui, Li, Minqi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675334/ https://www.ncbi.nlm.nih.gov/pubmed/36411860 http://dx.doi.org/10.2147/DDDT.S377001 |
Ejemplares similares
-
Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal
por: Kou, Yuying, et al.
Publicado: (2023) -
CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/β-Catenin Pathway in Osteoporosis
por: Wu, Wenbin, et al.
Publicado: (2020) -
Benzofuran pyran hybrid prevents glucocorticoid induced osteoporosis in mice via modulation of canonical Wnt/β-catenin signaling
por: Tripathi, Ashish Kumar, et al.
Publicado: (2022) -
Polygonatum sibiricum polysaccharide inhibits osteoporosis by promoting osteoblast formation and blocking osteoclastogenesis through Wnt/β-catenin signalling pathway
por: Du, Li, et al.
Publicado: (2016) -
ODP599 Modulation of Wnt/b-catenin and Autophagy in an in vitro Model of Glucocorticoid-induced Osteoporosis
por: Mannino, Federica, et al.
Publicado: (2022)