Functional expression and purification of DoxA, a key cytochrome P450 from Streptomyces peucetius ATCC 27952

The antitumor drug doxorubicin is widely used in clinical practice. However, the low yield and high cost of this drug highlight the urgent need for cost-effective processes to rapidly manufacture antitumor drugs at scale. In the biosynthesis pathway, the multi-functional cytochrome P450 enzyme DoxA...

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Detalles Bibliográficos
Autores principales: Yang, Liyan, Yang, Dengfeng, Wang, Qingyan, Li, Juan, Li, Hong-Liang, Pan, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675340/
https://www.ncbi.nlm.nih.gov/pubmed/36411834
http://dx.doi.org/10.7717/peerj.14373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675340/
https://www.ncbi.nlm.nih.gov/pubmed/36411834
http://dx.doi.org/10.7717/peerj.14373

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