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Dopamine-inhibited POMC(Drd2+) neurons in the ARC acutely regulate feeding and body temperature

Dopamine acts on neurons in the arcuate nucleus (ARC) of the hypothalamus, which controls homeostatic feeding responses. Here we demonstrate a differential enrichment of dopamine receptor 1 (Drd1) expression in food intake–promoting agouti related peptide (AgRP)/neuropeptide Y (NPY) neurons and a la...

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Detalles Bibliográficos
Autores principales: Gaziano, Isabella, Corneliussen, Svenja, Biglari, Nasim, Neuhaus, René, Shen, Linyan, Sotelo-Hitschfeld, Tamara, Klemm, Paul, Steuernagel, Lukas, De Solis, Alain J., Chen, Weiyi, Wunderlich, F. Thomas, Kloppenburg, Peter, Brüning, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675440/
https://www.ncbi.nlm.nih.gov/pubmed/36345942
http://dx.doi.org/10.1172/jci.insight.162753