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Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma

Thy-1 (CD90) is a well-known marker of fibroblasts implicated in organ fibrosis, but its contribution to skin fibrosis remains unknown. We examined Thy-1 expression in scleroderma skin and its potential role as a biomarker and pathogenic factor in animal models of skin fibrosis. Skin from patients w...

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Detalles Bibliográficos
Autores principales: Marangoni, Roberta G., Datta, Poulami, Paine, Ananta, Duemmel, Stacey, Nuzzo, Marc, Sherwood, Laura, Varga, John, Ritchlin, Christopher, Korman, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675443/
https://www.ncbi.nlm.nih.gov/pubmed/36066980
http://dx.doi.org/10.1172/jci.insight.149426