Cargando…
Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma
Thy-1 (CD90) is a well-known marker of fibroblasts implicated in organ fibrosis, but its contribution to skin fibrosis remains unknown. We examined Thy-1 expression in scleroderma skin and its potential role as a biomarker and pathogenic factor in animal models of skin fibrosis. Skin from patients w...
Autores principales: | Marangoni, Roberta G., Datta, Poulami, Paine, Ananta, Duemmel, Stacey, Nuzzo, Marc, Sherwood, Laura, Varga, John, Ritchlin, Christopher, Korman, Benjamin D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675443/ https://www.ncbi.nlm.nih.gov/pubmed/36066980 http://dx.doi.org/10.1172/jci.insight.149426 |
Ejemplares similares
-
Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis
por: Korman, Benjamin, et al.
Publicado: (2018) -
Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs
por: Marangoni, Roberta Goncalves, et al.
Publicado: (2020) -
Pyroptosis executor gasdermin D plays a key role in scleroderma and bleomycin-induced skin fibrosis
por: Yang, Huan, et al.
Publicado: (2022) -
MKP-1 Deficiency Exacerbates Skin Fibrosis in a Mouse Model of Scleroderma
por: Scotece, Morena, et al.
Publicado: (2023) -
Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts
por: Tsou, Pei-Suen, et al.
Publicado: (2014)