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Senescence plays a role in myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1; MIM #160900) is an autosomal dominant disorder, clinically characterized by progressive muscular weakness and multisystem degeneration. The broad phenotypes observed in patients with DM1 resemble the appearance of an accelerated aging process. However, the molecular m...

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Detalles Bibliográficos
Autores principales: García-Puga, Mikel, Saenz-Antoñanzas, Ander, Gerenu, Gorka, Arrieta-Legorburu, Alex, Fernández-Torrón, Roberto, Zulaica, Miren, Saenz, Amets, Elizazu, Joseba, Nogales-Gadea, Gisela, Gadalla, Shahinaz M., Araúzo-Bravo, Marcos J., López de Munain, Adolfo, Matheu, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675450/
https://www.ncbi.nlm.nih.gov/pubmed/36040809
http://dx.doi.org/10.1172/jci.insight.159357