Fcγ receptor–mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies

New strategies that augment T cell responses are required to broaden the therapeutic arsenal against cancer. CD96, TIGIT, and CD226 are receptors that bind to a communal ligand, CD155, and transduce either inhibitory or activating signals. The function of TIGIT and CD226 is established, whereas the...

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Detalles Bibliográficos
Autores principales: Rogel, Anne, Ibrahim, Fathima M., Thirdborough, Stephen M., Renart-Depontieu, Florence, Birts, Charles N., Buchan, Sarah L., Preville, Xavier, King, Emma V., Al-Shamkhani, Aymen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675451/
https://www.ncbi.nlm.nih.gov/pubmed/35998045
http://dx.doi.org/10.1172/jci.insight.158444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675451/
https://www.ncbi.nlm.nih.gov/pubmed/35998045
http://dx.doi.org/10.1172/jci.insight.158444

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