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Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells

Acute kidney injury (AKI) represents a common complication in critically ill patients that is associated with increased morbidity and mortality. In a murine AKI model induced by ischemia/reperfusion injury (IRI), we show that glutamine significantly decreases kidney damage and improves kidney functi...

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Detalles Bibliográficos
Autores principales: Thomas, Katharina, Zondler, Lisa, Ludwig, Nadine, Kardell, Marina, Lüneburg, Corinna, Henke, Katharina, Mersmann, Sina, Margraf, Andreas, Spieker, Tilmann, Tekath, Tobias, Velic, Ana, Holtmeier, Richard, Hermann, Juliane, Jankowski, Vera, Meersch, Melanie, Vestweber, Dietmar, Westphal, Martin, Roth, Johannes, Schäfers, Michael A., Kellum, John A., Lowell, Clifford A., Rossaint, Jan, Zarbock, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675453/
https://www.ncbi.nlm.nih.gov/pubmed/36107633
http://dx.doi.org/10.1172/jci.insight.163161