Cargando…
Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
Acute kidney injury (AKI) represents a common complication in critically ill patients that is associated with increased morbidity and mortality. In a murine AKI model induced by ischemia/reperfusion injury (IRI), we show that glutamine significantly decreases kidney damage and improves kidney functi...
Autores principales: | Thomas, Katharina, Zondler, Lisa, Ludwig, Nadine, Kardell, Marina, Lüneburg, Corinna, Henke, Katharina, Mersmann, Sina, Margraf, Andreas, Spieker, Tilmann, Tekath, Tobias, Velic, Ana, Holtmeier, Richard, Hermann, Juliane, Jankowski, Vera, Meersch, Melanie, Vestweber, Dietmar, Westphal, Martin, Roth, Johannes, Schäfers, Michael A., Kellum, John A., Lowell, Clifford A., Rossaint, Jan, Zarbock, Alexander |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675453/ https://www.ncbi.nlm.nih.gov/pubmed/36107633 http://dx.doi.org/10.1172/jci.insight.163161 |
Ejemplares similares
-
Remote ischemic preconditioning causes transient cell cycle arrest and renal protection by a NF-κB–dependent Sema5B pathway
por: Rossaint, Jan, et al.
Publicado: (2022) -
The Pathogenesis of Ischemia-Reperfusion Induced Acute Kidney Injury Depends on Renal Neutrophil Recruitment Whereas Sepsis-Induced AKI Does Not
por: Li, Zhenhan, et al.
Publicado: (2022) -
Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education
por: Rossaint, Jan, et al.
Publicado: (2021) -
Analysis of Leukocyte Recruitment in Continuous Veno-Venous Hemofiltration with Regional Citrate vs. Systemic Heparin Anticoagulation
por: Margraf, Andreas, et al.
Publicado: (2022) -
6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice
por: Margraf, Andreas, et al.
Publicado: (2018)