Cargando…

In vivo killing of primary HIV-infected cells by peripheral-injected early memory–enriched anti-HIV duoCAR T cells

HIV-specific chimeric antigen receptor–T cell (CAR T cell) therapies are candidates to functionally cure HIV infection in people with HIV (PWH) by eliminating reactivated HIV-infected cells derived from latently infected cells within the HIV reservoir. Paramount to translating such therapeutic candi...

Descripción completa

Detalles Bibliográficos
Autores principales: Anthony-Gonda, Kim, Ray, Alex, Su, Hang, Wang, Yuge, Xiong, Ying, Lee, Danica, Block, Ariele, Chilunda, Vanessa, Weiselberg, Jessica, Zemelko, Lily, Wang, Yen Y., Kleinsorge-Block, Sarah, Reese, Jane S., de Lima, Marcos, Ochsenbauer, Christina, Kappes, John C., Dimitrov, Dimiter S., Orentas, Rimas, Deeks, Steven G., Rutishauser, Rachel L., Berman, Joan W., Goldstein, Harris, Dropulić, Boro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675454/
https://www.ncbi.nlm.nih.gov/pubmed/36345941
http://dx.doi.org/10.1172/jci.insight.161698