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Endothelial cell polarity and extracellular matrix composition require functional ATP6AP2 during developmental and pathological angiogenesis

The (Pro)renin receptor ([P]RR), also known as ATP6AP2, is a single-transmembrane protein that is implicated in a multitude of biological processes. However, the exact role of ATP6AP2 during blood vessel development remains largely undefined. Here, we use an inducible endothelial cell–specific (EC-s...

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Detalles Bibliográficos
Autores principales: Patel, Nehal R., K C, Rajan, Blanks, Avery, Li, Yisu, Prieto, Minolfa C., Meadows, Stryder M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675464/
https://www.ncbi.nlm.nih.gov/pubmed/35998033
http://dx.doi.org/10.1172/jci.insight.154379