Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury

Lipoprotein modification by reactive dicarbonyls, including isolevuglandin (IsoLG), produces dysfunctional particles. Kidneys participate in lipoprotein metabolism, including tubular uptake. However, the process beyond the proximal tubule is unclear, as is the effect of kidney injury on this pathway...

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Detalles Bibliográficos
Autores principales: Zhong, Jianyong, Yang, Hai-Chun, Shelton, Elaine L., Matsusaka, Taiji, Clark, Amanda J., Yermalitsky, Valery, Mashhadi, Zahra, May-Zhang, Linda S., Linton, MacRae F., Fogo, Agnes B., Kirabo, Annet, Davies, Sean S., Kon, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675465/
https://www.ncbi.nlm.nih.gov/pubmed/36125905
http://dx.doi.org/10.1172/jci.insight.161878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675465/
https://www.ncbi.nlm.nih.gov/pubmed/36125905
http://dx.doi.org/10.1172/jci.insight.161878

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