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Cell-free and alkylated hemoproteins improve survival in mouse models of carbon monoxide poisoning

I.v. administration of a high-affinity carbon monoxide–binding (CO-binding) molecule, recombinant neuroglobin, can improve survival in CO poisoning mouse models. The current study aims to discover how biochemical variables of the scavenger determine the CO removal from the RBCs by evaluating 3 readi...

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Detalles Bibliográficos
Autores principales: Xu, Qinzi, Rose, Jason J., Chen, Xiukai, Wang, Ling, DeMartino, Anthony W., Dent, Matthew R., Tiwari, Sagarika, Bocian, Kaitlin, Huang, Xueyin N., Tong, Qin, McTiernan, Charles F., Guo, Lanping, Alipour, Elmira, Jones, Trevor C., Ucer, K. Burak, Kim-Shapiro, Daniel B., Tejero, Jesús, Gladwin, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675481/
https://www.ncbi.nlm.nih.gov/pubmed/36173682
http://dx.doi.org/10.1172/jci.insight.153296