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Chitinase 3 like 1 contributes to the development of pulmonary vascular remodeling in pulmonary hypertension

Chitinase 3 like 1 (CHI3L1) is the prototypic chitinase-like protein mediating inflammation, cell proliferation, and tissue remodeling. Limited data suggest CHI3L1 is elevated in human pulmonary arterial hypertension (PAH) and is associated with disease severity. Despite its importance as a regulato...

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Detalles Bibliográficos
Autores principales: Sun, Xiuna, Nakajima, Erika, Norbrun, Carmelissa, Sorkhdini, Parand, Yang, Alina Xiaoyu, Yang, Dongqin, Ventetuolo, Corey E., Braza, Julie, Vang, Alexander, Aliotta, Jason, Banerjee, Debasree, Pereira, Mandy, Baird, Grayson, Lu, Qing, Harrington, Elizabeth O., Rounds, Sharon, Lee, Chun Geun, Yao, Hongwei, Choudhary, Gaurav, Klinger, James R., Zhou, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675485/
https://www.ncbi.nlm.nih.gov/pubmed/35951428
http://dx.doi.org/10.1172/jci.insight.159578