ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion

Macrophages in the tumor microenvironment have a substantial impact on tumor progression. Depending on the signaling environment in the tumor, macrophages can either support or constrain tumor progression. It is therefore of therapeutic interest to identify the tumor-derived factors that control mac...

Descripción completa

Detalles Bibliográficos
Autores principales: Gnosa, Sebastian P., Puig Blasco, Laia, Piotrowski, Krzysztof B., Freiberg, Marie L., Savickas, Simonas, Madsen, Daniel H., auf dem Keller, Ulrich, Kronqvist, Pauliina, Kveiborg, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675555/
https://www.ncbi.nlm.nih.gov/pubmed/35998057
http://dx.doi.org/10.1172/jci.insight.155296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675555/
https://www.ncbi.nlm.nih.gov/pubmed/35998057
http://dx.doi.org/10.1172/jci.insight.155296

Ejemplares similares