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Statin shapes inflamed tumor microenvironment and enhances immune checkpoint blockade in non–small cell lung cancer

Immune checkpoint blockade (ICB) therapy has achieved breakthroughs in the treatment of advanced non–small cell lung cancer (NSCLC). Nevertheless, the low response due to immuno-cold (i.e., tumors with limited tumor-infiltrating lymphocytes) tumor microenvironment (TME) largely limits the applicatio...

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Detalles Bibliográficos
Autores principales: Mao, Wenjun, Cai, Yun, Chen, Danrong, Jiang, Guanyu, Xu, Yongrui, Chen, Ruo, Wang, Fengxu, Wang, Xuehai, Zheng, Mingfeng, Zhao, Xinyuan, Mei, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675559/
https://www.ncbi.nlm.nih.gov/pubmed/35943796
http://dx.doi.org/10.1172/jci.insight.161940