SARA suppresses myofibroblast precursor transdifferentiation in fibrogenesis in a mouse model of scleroderma

We previously reported that Smad anchor for receptor activation (SARA) plays a critical role in maintaining epithelial cell phenotype. Here, we show that SARA suppressed myofibroblast precursor transdifferentiation in a mouse model of scleroderma. Mice overexpressing SARA specifically in PDGFR-β(+)...

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Detalles Bibliográficos
Autores principales: Corano Scheri, Katia, Liang, Xiaoyan, Dalal, Vidhi, Le Poole, I. Caroline, Varga, John, Hayashida, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675568/
https://www.ncbi.nlm.nih.gov/pubmed/36136606
http://dx.doi.org/10.1172/jci.insight.160977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675568/
https://www.ncbi.nlm.nih.gov/pubmed/36136606
http://dx.doi.org/10.1172/jci.insight.160977

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