Impaired fatty acid metabolism perpetuates lipotoxicity along the transition to chronic kidney injury

Energy metabolism failure in proximal tubule cells (PTCs) is a hallmark of chronic kidney injury. We combined transcriptomic, metabolomic, and lipidomic approaches in experimental models and patient cohorts to investigate the molecular basis of the progression to chronic kidney allograft injury init...

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Detalles Bibliográficos
Autores principales: Rinaldi, Anna, Lazareth, Hélène, Poindessous, Virginie, Nemazanyy, Ivan, Sampaio, Julio L., Malpetti, Daniele, Bignon, Yohan, Naesens, Maarten, Rabant, Marion, Anglicheau, Dany, Cippà, Pietro E., Pallet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675570/
https://www.ncbi.nlm.nih.gov/pubmed/35998043
http://dx.doi.org/10.1172/jci.insight.161783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675570/
https://www.ncbi.nlm.nih.gov/pubmed/35998043
http://dx.doi.org/10.1172/jci.insight.161783

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