Structure of the human heparan sulfate polymerase complex EXT1-EXT2

Heparan sulfates are complex polysaccharides that mediate the interaction with a broad range of protein ligands at the cell surface. A key step in heparan sulfate biosynthesis is catalyzed by the bi-functional glycosyltransferases EXT1 and EXT2, which generate the glycan backbone consisting of repea...

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Detalles Bibliográficos
Autores principales: Leisico, Francisco, Omeiri, Juneina, Le Narvor, Christine, Beaudouin, Joël, Hons, Michael, Fenel, Daphna, Schoehn, Guy, Couté, Yohann, Bonnaffé, David, Sadir, Rabia, Lortat-Jacob, Hugues, Wild, Rebekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675754/
https://www.ncbi.nlm.nih.gov/pubmed/36402845
http://dx.doi.org/10.1038/s41467-022-34882-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675754/
https://www.ncbi.nlm.nih.gov/pubmed/36402845
http://dx.doi.org/10.1038/s41467-022-34882-6

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