Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA.4/5/2.75 subvariants in BA.2 breakthrough infections

With declining SARS-CoV-2-specific antibody titers and increasing numbers of spike mutations, the ongoing emergence of Omicron subvariants causes serious challenges to current vaccination strategies. BA.2 breakthrough infections have occurred in people who have received the wild-type vaccines, inclu...

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Detalles Bibliográficos
Autores principales: Ju, Bin, Fan, Qing, Wang, Miao, Liao, Xuejiao, Guo, Huimin, Wang, Haiyan, Ge, Xiangyang, Liu, Lei, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675777/
https://www.ncbi.nlm.nih.gov/pubmed/36402756
http://dx.doi.org/10.1038/s41467-022-34400-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675777/
https://www.ncbi.nlm.nih.gov/pubmed/36402756
http://dx.doi.org/10.1038/s41467-022-34400-8

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